Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments.

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Receptor binding activity of lipid recombinants of apolipoprotein B-100 thrombolytic fragments.

Apolipoprotein (apo) B-100, the protein constituent of low density lipoproteins (LDL), is the determinant responsible for LDL binding to the apoB,E(LDL) receptor on cells. The current study was designed to identify the region(s) of apoB-100 that interact with the apoB,E(LDL) receptor. Apolipoprotein B-100 was fragmented by thrombin digestion, and the isolated fragments (T2, T3, T4) were recombi...

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ژورنال

عنوان ژورنال: Journal of Lipid Research

سال: 1987

ISSN: 0022-2275

DOI: 10.1016/s0022-2275(20)38571-0